CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL

Catalog number BNC882027-100

Price for BNC882027-100

Size / count 1x 100 µL

About this product

Recognizes the CD45 leukocyte common antigen (LCA) family which is comprised of at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portions of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms. A positive result with this MAb is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC882027-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: B220; CD45R; GP180; Leukocyte common antigen (LCA) ; Loc; Ly-5; Lyt-4; Protein tyrosine phosphatase receptor type C (PTPRC) ; Receptor-type tyrosine-protein phosphatase C; T200 glycoprotein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PTPRC
Gene ID: 5788
NCBI Gene ID: 654514
UniProt: P08575
Swiss Prot: P08575
Host: Mouse
Species Reactivity: Human
Reactivity: CD45|LCA
Immunogen: Human recombinant full-length CD45 protein
Target Antigen: CD45 | LCA
Clonality: Monoclonal
Clone: PTPRC/1147 PTPRC/1460
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Immunology, Signal transduction
Positive Control: Ramos, U-698, or GA-10 cells. Tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 180-220 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL?

The catalog number for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL is BNC882027-100.

What sizes are available for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL?

CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL in stock?

CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL?

CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL?

The safety data sheet for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF488A conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.