ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL

Catalog number BNC402047-100

Price for BNC402047-100

Size / count 1x 100 µL

About this product

ZAP70 is a 70 kDa protein tyrosine kinase found in T-cells and natural killer cells. Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well. Anti-ZAP70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP70 negative) and Ig-unmutated (anti-ZAP70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC402047-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Selective T cell defect; SRK; STD; Syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70; TZK; Zeta chain associated protein kinase 70kDa
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ZAP70
Gene ID: 7535
NCBI Gene ID: 234569
UniProt: P43403
Swiss Prot: P43403
Host: Mouse
Species Reactivity: Human
Reactivity: ZAP70
Immunogen: Recombinant fragment (around aa 247-382) of human ZAP70 protein (exact sequence is proprietary)
Target Antigen: ZAP70
Clonality: Monoclonal
Clone: ZAP70/2047
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified)
Positive Control: Jurkat cells. Tonsil or lymph node.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 70 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL?

The catalog number for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL is BNC402047-100.

What sizes are available for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL?

ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL in stock?

ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL?

ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL?

The safety data sheet for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF640R conjugate, 0.1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.