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Product details

ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL

Catalog number BNC942047-100

Price for BNC942047-100

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Size / count 1x 100 µL

About this product

ZAP70 is a 70 kDa protein tyrosine kinase found in T-cells and natural killer cells. Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well. Anti-ZAP70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP70 negative) and Ig-unmutated (anti-ZAP70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC942047-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Selective T cell defect; SRK; STD; Syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70; TZK; Zeta chain associated protein kinase 70kDa
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ZAP70
Gene ID
7535
NCBI Gene ID
234569
UniProt
P43403
Swiss Prot
P43403
Host
Mouse
Species Reactivity
Human
Reactivity
ZAP70
Immunogen
Recombinant fragment (around aa 247-382) of human ZAP70 protein (exact sequence is proprietary)
Target Antigen
ZAP70
Clonality
Monoclonal
Clone
ZAP70/2047
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified)
Positive Control
Jurkat cells. Tonsil or lymph node.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
70 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL?

The catalog number for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL is BNC942047-100.

What sizes are available for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL?

ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL in stock?

ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL?

ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL?

The safety data sheet for ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e1010fe/msds/bnc942047-100.pdf.

What is ZAP70 (Chronic Lymphocytic Leukemia Marker) (ZAP70/2047), CF594 conjugate, 0.1mg/mL used for?

ZAP70 is a 70 kDa protein tyrosine kinase found in T-cells and natural killer cells. Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well. Anti-ZAP70 expression is an excellent

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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