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Product details
Catalog number BNUM2053-50
Price for BNUM2053-50
Size / count 1x 50 µL
This antibody recognizes a 33 kDa glycoprotein, identified as Nucleophosmin (NPM) . It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Nucleophosmin (Acute Myeloid Leukemia Marker) (NA24), 1mg/mL is BNUM2053-50.
Nucleophosmin (Acute Myeloid Leukemia Marker) (NA24), 1mg/mL is available in the following size(s): 1x 50 µL.
Nucleophosmin (Acute Myeloid Leukemia Marker) (NA24), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Nucleophosmin (Acute Myeloid Leukemia Marker) (NA24), 1mg/mL is manufactured by Biotium.
Estimated delivery time for Nucleophosmin (Acute Myeloid Leukemia Marker) (NA24), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Nucleophosmin (Acute Myeloid Leukemia Marker) (NA24), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e101942/msds/bnum2053-50.pdf.
This antibody recognizes a 33 kDa glycoprotein, identified as Nucleophosmin (NPM) . It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis.
Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.
Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.
If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.
