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Product details

CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL

Catalog number BNUB2056-100

Price for BNUB2056-100

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Size / count 1x 100 µL

About this product

Recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9) . CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2056-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
GP40; Leu9; p41; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD7
Gene ID
924
NCBI Gene ID
186820
UniProt
P09564
Swiss Prot
P09564
Host
Mouse
Species Reactivity
Human
Reactivity
CD7
Immunogen
Recombinant human full-length CD7 protein
Target Antigen
CD7
Clonality
Monoclonal
Clone
CD7/3737
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Immunology, Signal transduction
Positive Control
Jurkat or Molt-4 cells. Human peripheral blood lymphocytes.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
40 kDa
References & Citations
Saxena A, et al. Biologic and clinical significance of CD7 expression in acute myeloid leukemia. Am J Hematol. 1998;58(4):278-84.
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL?

The catalog number for CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL is BNUB2056-100.

What sizes are available for CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL?

CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL in stock?

CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL?

CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL?

Estimated delivery time for CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL?

The safety data sheet for CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD7 (T-Cell Leukemia Marker) (CD7/3737), 0.2mg/mL used for?

Recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9) . CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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