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Product details

DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL

Catalog number BNC882061-100

Price for BNC882061-100

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Size / count 1x 100 µL

About this product

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC882061-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ADCADN; AIM; CXXC-type zinc finger protein 9; CXXC9; DNA methyltransferase 1 (DNMT1) ; HSN1E; MCMT; Met1; MommeD2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
DNMT1
Gene ID
1786
NCBI Gene ID
202672
UniProt
P26358
Swiss Prot
P26358
Host
Mouse
Species Reactivity
Human
Reactivity
DNA Methyltransferase 1|DNMT1
Immunogen
Recombinant human DNMT1 protein fragment (around aa 767-912) (exact sequence is proprietary)
Target Antigen
DNA Methyltransferase 1 | DNMT1
Clonality
Monoclonal
Clone
DNMT1/2061
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Raji cells. Tonsil or Placenta.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
184 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL?

The catalog number for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL is BNC882061-100.

What sizes are available for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL?

DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL in stock?

DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL?

DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL?

The safety data sheet for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), CF488A conjugate, 0.1mg/mL used for?

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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