DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2061-500

Price for BNCB2061-500

Size / count 1x 500 µL

About this product

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2061-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ADCADN; AIM; CXXC-type zinc finger protein 9; CXXC9; DNA methyltransferase 1 (DNMT1) ; HSN1E; MCMT; Met1; MommeD2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: DNMT1
Gene ID: 1786
NCBI Gene ID: 202672
UniProt: P26358
Swiss Prot: P26358
Host: Mouse
Species Reactivity: Human
Reactivity: DNA Methyltransferase 1|DNMT1
Immunogen: Recombinant human DNMT1 protein fragment (around aa 767-912) (exact sequence is proprietary)
Target Antigen: DNA Methyltransferase 1 | DNMT1
Clonality: Monoclonal
Clone: DNMT1/2061
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Raji cells. Tonsil or Placenta.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 184 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL?

The catalog number for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL is BNCB2061-500.

What sizes are available for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL?

DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL in stock?

DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL?

DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL?

The safety data sheet for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), Biotin conjugate, 0.1mg/mL used for?

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.