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Product details

DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL

Catalog number BNUM2061-50

Price for BNUM2061-50

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Size / count 1x 50 µL

About this product

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM2061-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ADCADN; AIM; CXXC-type zinc finger protein 9; CXXC9; DNA methyltransferase 1 (DNMT1) ; HSN1E; MCMT; Met1; MommeD2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
DNMT1
Gene ID
1786
NCBI Gene ID
202672
UniProt
P26358
Swiss Prot
P26358
Host
Mouse
Species Reactivity
Human
Reactivity
DNA Methyltransferase 1|DNMT1
Immunogen
Recombinant human DNMT1 protein fragment (around aa 767-912) (exact sequence is proprietary)
Target Antigen
DNA Methyltransferase 1 | DNMT1
Clonality
Monoclonal
Clone
DNMT1/2061
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Raji cells. Tonsil or Placenta.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
184 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL?

The catalog number for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL is BNUM2061-50.

What sizes are available for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL?

DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL is available in the following size(s): 1x 50 µL.

Is DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL in stock?

DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL?

DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL?

Estimated delivery time for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL?

The safety data sheet for DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is DNMT1 / DNA Methyltransferase 1 (DNMT1/2061), 1mg/mL used for?

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

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