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Product details
Catalog number BNUM2067-50
Price for BNUM2067-50
Size / count 1x 50 µL
This antibody recognizes a protein of 120-80 kDa, identified as E-cadherin. Cadherins comprise a family of calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as beta-catenin, to regulate cadherin function. E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combination with p120 Catenin, it is useful for the differentiation between ductal (E-cadherin) and lobular (E-cadherin -) breast carcinomas. It may also help in diagnosis of mesothelioma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (rCDH1/1525), 1mg/mL is BNUM2067-50.
E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (rCDH1/1525), 1mg/mL is available in the following size(s): 1x 50 µL.
E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (rCDH1/1525), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (rCDH1/1525), 1mg/mL is manufactured by Biotium.
Estimated delivery time for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (rCDH1/1525), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (rCDH1/1525), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100e50/msds/bnum2067-50.pdf.
This antibody recognizes a protein of 120-80 kDa, identified as E-cadherin. Cadherins comprise a family of calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin
Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.
Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
