Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL

Catalog number BNC042081-500

Price for BNC042081-500

Size / count 1x 500 µL

About this product

Mammalian ferritins consist of 24 subunits made up of 2 types of poly-peptide chains, ferritin heavy chain and ferritin light chain, which each have unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidationof FeI (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III) . The most prominent role of mammalian ferritins is to provide iron-buffering capacity to cells. In addition to iron buffering, heavy chain ferritin is also involved in the regulation of thymidine biosynthesis via increased expression of cytoplasmic serine hydroxymethyltransferase, which is a limiting factor in thymidylate synthesis in MCF-7 cells. Light chain ferritin is involved in cataracts by at least two mechanisms: hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed; and oxidative stress, an important factor in the development of aging-related cataracts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042081-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Apoferritin; Cell proliferation-inducing gene 15 protein; Ferritin H subunit; Ferritin heavy chain; FHC; FRIH; FTH1; FTHL6; Iron overload autosomal dominant; PIG15; Placenta immunoregulatory factor; Proliferation inducing gene 15 protein (PLIF)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FTH1
Gene ID: 2495
NCBI Gene ID: 524910; 645560
UniProt: P02794
Swiss Prot: P02794
Host: Mouse
Species Reactivity: Human
Reactivity: Ferritin, Heavy Chain
Immunogen: Recombinant human FTH1 protein fragment (around aa 58-180) (exact sequence is proprietary)
Target Antigen: Ferritin, Heavy Chain
Clonality: Monoclonal
Clone: FTH/2081
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 21 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL?

The catalog number for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL is BNC042081-500.

What sizes are available for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL?

Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL in stock?

Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL?

Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF405S conjugate, 0.1mg/mL used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.