HNF1A (Pancreatic Tumor Suppressor) (HNF1A/2087), 1mg/mL

About this product

HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicated HNF1Aas a susceptibility gene for pancreatic cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNUM2087-50

Size / count

1x 50 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

Albumin proximal factor; Hepatic nuclear factor 1 alpha; Hepatic transcription factor 1 alpha; HNF-1A; Interferon production regulator factor; LFB1; LFB1 hepatic nuclear factor; Liver specific transcription factor LFB1; Maturity onset diabetes of the young 3 (MODY3) ; TCF1; Transcription factor 1 hepatic

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

HNF1A

Gene ID

6927

NCBI Gene ID

654455

UniProt

P20823

Swiss Prot

P20823

Host

Mouse

Species Reactivity

Human

Reactivity

HNF1A

Immunogen

Recombinant fragment (around aa 214-339) of human HNF1A protein (exact sequence is proprietary)

Target Antigen

HNF1A

Clonality

Monoclonal

Clone

HNF1A/2087

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified)

Positive Control

Jurkat cells. Small Intestine or Pancreas.

Stability

2 years

Concentration

1 mg/mL

Buffer

PBS, no BSA, no azide

Molecular Weight

79 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse)

Classification

PBS, no BSA, no sodium azide (CAS 26628-22-8)

Conjugate

Purified, BSA-free