Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL

Catalog number BNC942115-100

Price for BNC942115-100

Size / count 1x 100 µL

About this product

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18) . CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19) . Reportedly, anti-CK8 is useful for the differentiation of lobular ('ring-like, perinuclear') from ductal ('peripheral-predominant') carcinoma of the breast. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC942115-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CARD2; CK8; CYK8; CYKER; Cytokeratin Endo A; DreK8; EndoA; K2C8; K8; Keratin 8; Krt 2.8; KRT8; Type-II Keratin Kb8
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KRT8
Gene ID: 3856
NCBI Gene ID: 533782; 708445
UniProt: P05787
Swiss Prot: P05787
Host: Mouse
Species Reactivity: Human
Reactivity: Cytokeratin 8
Immunogen: Recombinant full-length human KRT8 protein
Target Antigen: Cytokeratin 8
Clonality: Monoclonal
Clone: KRT8/2115
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Cytoskeleton
Positive Control: MCF-7 , HeLa or A431 cells. Skin, colon, lung or breast carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 52.5 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL?

The catalog number for Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL is BNC942115-100.

What sizes are available for Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL?

Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL in stock?

Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL?

Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin 8 (KRT8) (KRT8/2115), CF594 conjugate, 0.1mg/mL used for?

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.