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Product details

Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL

Catalog number BNUM2122-50

Price for BNUM2122-50

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Size / count 1x 50 µL

About this product

Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM2122-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Epididymis secretory protein Li 50; Polyubiquitin B; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2; Ubiquitin; Ubiquitin B
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
UBB
Gene ID
7314
NCBI Gene ID
356190 and 520348
UniProt
P0CG47; P0CG48; P62979; P62987 and P62988
Swiss Prot
P0CG47; P0CG48; P62979; P62987 and P62988
Host
Mouse
Species Reactivity
Human
Reactivity
Ubiquitin
Immunogen
Recombinant fragment of human Ubiquitin protein (around aa 1-119) (exact sequence is proprietary)
Target Antigen
Ubiquitin
Clonality
Monoclonal
Clone
UBB/2122
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Ubiquitination
Positive Control
HeLa or Jurkat cells. Alzheimer s Brain
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
9 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL?

The catalog number for Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL is BNUM2122-50.

What sizes are available for Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL?

Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL in stock?

Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL?

Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL?

Estimated delivery time for Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL?

The safety data sheet for Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Ubiquitin (Autophagy Marker) (UBB/2122), 1mg/mL used for?

Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin lig

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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