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Product details

Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL

Catalog number BNUB2161-500

Price for BNUB2161-500

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Size / count 1x 500 µL

About this product

MAb r2H11 reacts with a partially defined epitope of human thyroglobulin. This epitope is different form the epitope recognized by MAb 6E1. Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2161-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
AITD3; hTG; TDH3; Tg; Tgn
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TG
Gene ID
7038
NCBI Gene ID
654591
UniProt
P01266
Swiss Prot
P01266
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
Thyroglobulin
Immunogen
Human thyroid follicular cells
Target Antigen
Thyroglobulin
Clonality
Recombinant Monoclonal
Clone
R2H11
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Thyroid
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
660 kDa (Dimeric Form)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL?

The catalog number for Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL is BNUB2161-500.

What sizes are available for Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL?

Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL in stock?

Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL?

Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL?

Estimated delivery time for Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL?

The safety data sheet for Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e100fb8/msds/bnub2161-500.pdf.

What is Thyroglobulin (Thyroidal Cell Marker) (r2H11), 0.2mg/mL used for?

MAb r2H11 reacts with a partially defined epitope of human thyroglobulin. This epitope is different form the epitope recognized by MAb 6E1. Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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