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Product details

CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL

Catalog number BNUM2164-50

Price for BNUM2164-50

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Size / count 1x 50 µL

About this product

This MAb recognizes a protein of 140 kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM2164-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD163; CD163 antigen; Macrophage-associated antigen; M130; CD163 molecule; Hemoglobin scavenger receptor; MM130; Scavenger receptor cysteine rich type 1 protein M130
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD163
Gene ID
9332
NCBI Gene ID
504641
UniProt
Q86V7
Swiss Prot
Q86V7
Host
Mouse
Species Reactivity
Human
Reactivity
CD163
Immunogen
Recombinant fragment of human CD163 protein (around aa 43-196) (exact sequence is proprietary)
Target Antigen
CD163
Clonality
Monoclonal
Clone
M130/2164
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
hPBL Cells. Skin, Lung, Placenta or Histiocytoma.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
140 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL?

The catalog number for CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL is BNUM2164-50.

What sizes are available for CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL?

CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL in stock?

CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL?

CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL?

Estimated delivery time for CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL?

The safety data sheet for CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101f3e/msds/bnum2164-50.pdf.

What is CD163 (Monocyte & Macrophage Marker) (M130/2164), 1mg/mL used for?

This MAb recognizes a protein of 140 kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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