Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL

Catalog number BNC042179-500

Price for BNC042179-500

Size / count 1x 500 µL

About this product

Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL) . Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042179-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Annexin-1; Calpactin-2; Chromobindin-9; Phospholipase A2 inhibitory protein; LPC1; p35
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ANXA1
Gene ID: 301
NCBI Gene ID: 494173
UniProt: P04083
Swiss Prot: P04083
Host: Mouse
Species Reactivity: Human
Reactivity: Annexin A1
Immunogen: Mixture of native proteins from human bone tissues
Target Antigen: Annexin A1
Clonality: Monoclonal
Clone: 6E4/3
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IHC, FFPE (verified)
Positive Control: HeLa, A431, K562 cells; human esophagus, placenta and prostate tissues.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 35 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL?

The catalog number for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL is BNC042179-500.

What sizes are available for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL?

Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL in stock?

Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL?

Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF405S conjugate, 0.1mg/mL used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.