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Product details

Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL

Catalog number BNC472179-100

Price for BNC472179-100

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Size / count 1x 100 µL

About this product

Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL) . Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC472179-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Annexin-1; Calpactin-2; Chromobindin-9; Phospholipase A2 inhibitory protein; LPC1; p35
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ANXA1
Gene ID
301
NCBI Gene ID
494173
UniProt
P04083
Swiss Prot
P04083
Host
Mouse
Species Reactivity
Human
Reactivity
Annexin A1
Immunogen
Mixture of native proteins from human bone tissues
Target Antigen
Annexin A1
Clonality
Monoclonal
Clone
6E4/3
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IHC, FFPE (verified)
Positive Control
HeLa, A431, K562 cells; human esophagus, placenta and prostate tissues.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
35 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL?

The catalog number for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL is BNC472179-100.

What sizes are available for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL?

Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL in stock?

Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL?

Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a1061270361e104341/msds/bnc472179-100.pdf.

What is Annexin A1 / (Hairy Cell Leukemia Marker) (6E4/3), CF647 conjugate, 0.1mg/mL used for?

Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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