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Product details

EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL

Catalog number BNC942180-100

Price for BNC942180-100

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Size / count 1x 100 µL

About this product

This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC942180-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ERBB1; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
EGFR
Gene ID
1956
NCBI Gene ID
488293
UniProt
P00533
Swiss Prot
P00533
Host
Mouse
Species Reactivity
Human
Reactivity
EGFR
Immunogen
A synthetic peptide corresponding to aa 985-996 of human EGFR
Target Antigen
EGFR
Clonality
Monoclonal
Clone
F4
Type
Primary
Source
Animal
Origin
Animal
Applications
WB (verified)
Positive Control
A431 cells. Placenta, Breast, Colon or Bladder Carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~170 kDa (wild type) and ~145 kDa (vIII variant)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL?

The catalog number for EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL is BNC942180-100.

What sizes are available for EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL?

EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL in stock?

EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL?

EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL?

The safety data sheet for EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is EGFR (Epidermal Growth Factor Receptor) (F4), CF594 conjugate, 0.1mg/mL used for?

This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacell

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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