Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL

Catalog number BNC882183-100

Price for BNC882183-100

Size / count 1x 100 µL

About this product

Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of Occludin. Expression of Occludin is upregulated by polyunsaturated fatty acids, increasing trans-endothelial cell resistance and reducing cellular permeability to large molecules. The level of Occludin varies greatly depending on tissue; in brain tissue, Occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial Occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC882183-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BLCPMG; Occludin; OCLN; Phosphatase 1 regulatory subunit 115; PPP1R115; PTORCH1; Tight junction protein occludin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: OCLN
Gene ID: 100506658
NCBI Gene ID: 592605
UniProt: Q16625
Swiss Prot: Q16625
Host: Mouse
Species Reactivity: Human
Reactivity: Occludin
Immunogen: Recombinant human Occludin fragment around aa 282-415 (Exact sequence is proprietary)
Target Antigen: Occludin
Clonality: Monoclonal
Clone: OCLN/2183
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: HepG2 cells. Kidney.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 60-82 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL?

The catalog number for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL is BNC882183-100.

What sizes are available for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL?

Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL in stock?

Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL?

Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e102234/msds/bnc882183-100.pdf.

What is Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), CF488A conjugate, 0.1mg/mL used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.