Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL

Catalog number BNUM2183-50

Price for BNUM2183-50

Size / count 1x 50 µL

About this product

Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of Occludin. Expression of Occludin is upregulated by polyunsaturated fatty acids, increasing trans-endothelial cell resistance and reducing cellular permeability to large molecules. The level of Occludin varies greatly depending on tissue; in brain tissue, Occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial Occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM2183-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BLCPMG; Occludin; OCLN; Phosphatase 1 regulatory subunit 115; PPP1R115; PTORCH1; Tight junction protein occludin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: OCLN
Gene ID: 100506658
NCBI Gene ID: 592605
UniProt: Q16625
Swiss Prot: Q16625
Host: Mouse
Species Reactivity: Human
Reactivity: Occludin
Immunogen: Recombinant human Occludin fragment around aa 282-415 (Exact sequence is proprietary)
Target Antigen: Occludin
Clonality: Monoclonal
Clone: OCLN/2183
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: HepG2 cells. Kidney.
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 60-82 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL?

The catalog number for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL is BNUM2183-50.

What sizes are available for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL?

Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL in stock?

Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL?

Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL?

Estimated delivery time for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL?

The safety data sheet for Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100850/msds/bnum2183-50.pdf.

What is Occludin (OCLN) (Tight Junctions Marker) (OCLN/2183), 1mg/mL used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.