Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL

Catalog number BNC472190-500

Price for BNC472190-500

Size / count 1x 500 µL

About this product

Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472190-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CyaY; d-FXN; FARR; Frataxin mature form; Frataxin (81-210) ; FRDA; Friedreich ataxia protein; Fxn; i-FXN; m56-FXN; m78-FXN; m81-FXN; X25
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FXN
Gene ID: 2395
NCBI Gene ID: 20685
UniProt: Q16595
Swiss Prot: Q16595
Host: Mouse
Species Reactivity: Human
Reactivity: Faxin
Immunogen: Recombinant fragment of human Frataxin (FXN) protein (around aa 57-210) (exact sequence is proprietary)
Target Antigen: Faxin
Clonality: Monoclonal
Clone: FXN/2124
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: HepG2, Panc-2, HL-60 or HEK293 cells. Pancreas and Liver.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 14 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL?

The catalog number for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL is BNC472190-500.

What sizes are available for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL?

Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL in stock?

Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL?

Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e1011e9/msds/bnc472190-500.pdf.

What is Frataxin (Marker of Friedreich Ataxia) (FXN/2124), CF647 conjugate, 0.1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.