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Product details

Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2190-100

Price for BNCB2190-100

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Size / count 1x 100 µL

About this product

Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2190-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CyaY; d-FXN; FARR; Frataxin mature form; Frataxin (81-210) ; FRDA; Friedreich ataxia protein; Fxn; i-FXN; m56-FXN; m78-FXN; m81-FXN; X25
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
FXN
Gene ID
2395
NCBI Gene ID
20685
UniProt
Q16595
Swiss Prot
Q16595
Host
Mouse
Species Reactivity
Human
Reactivity
Faxin
Immunogen
Recombinant fragment of human Frataxin (FXN) protein (around aa 57-210) (exact sequence is proprietary)
Target Antigen
Faxin
Clonality
Monoclonal
Clone
FXN/2124
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
HepG2, Panc-2, HL-60 or HEK293 cells. Pancreas and Liver.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
14 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL?

The catalog number for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL is BNCB2190-100.

What sizes are available for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL?

Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL in stock?

Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL?

Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Frataxin (Marker of Friedreich Ataxia) (FXN/2124), Biotin conjugate, 0.1mg/mL used for?

Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possi

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

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