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Product details

NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2198-100

Price for BNCB2198-100

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Size / count 1x 100 µL

About this product

Expression of NKX2. 2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2. 2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2198-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Homeobox protein NK-2 homolog B; NK2 transcription factor like protein B; NK2 transcription factor related locus 2; NKX22; Nkx2b; tinman
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NKX2-2
Gene ID
4821
NCBI Gene ID
516922
UniProt
O95096
Swiss Prot
O95096
Host
Rabbit
Species Reactivity
Human
Reactivity
NKX2.2
Immunogen
Recombinant human NKX2.2 protein fragment (around aa1-119) (exact sequence is proprietary)
Target Antigen
NKX2.2
Clonality
Monoclonal
Clone
NX2/2198R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Pancreas or Ewing's sarcoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
40-50 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL?

The catalog number for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL is BNCB2198-100.

What sizes are available for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL?

NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL in stock?

NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL?

NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), Biotin conjugate, 0.1mg/mL used for?

Expression of NKX2. 2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2. 2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be di

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

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