NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL

Catalog number BNUM2198-50

Price for BNUM2198-50

Size / count 1x 50 µL

About this product

Expression of NKX2. 2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2. 2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM2198-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Homeobox protein NK-2 homolog B; NK2 transcription factor like protein B; NK2 transcription factor related locus 2; NKX22; Nkx2b; tinman
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NKX2-2
Gene ID: 4821
NCBI Gene ID: 516922
UniProt: O95096
Swiss Prot: O95096
Host: Rabbit
Species Reactivity: Human
Reactivity: NKX2.2
Immunogen: Recombinant human NKX2.2 protein fragment (around aa1-119) (exact sequence is proprietary)
Target Antigen: NKX2.2
Clonality: Monoclonal
Clone: NX2/2198R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Pancreas or Ewing's sarcoma
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 40-50 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Rabbit Monoclonal Antibody
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL?

The catalog number for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL is BNUM2198-50.

What sizes are available for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL?

NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL is available in the following size(s): 1x 50 µL.

Is NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL in stock?

NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL?

NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL?

Estimated delivery time for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL?

The safety data sheet for NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (NX2/2198R), 1mg/mL used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.