Product details
Catalog number BNC882223-100
Price for BNC882223-100
Size / count 1x 100 µL
Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. Expression of the ANXA1 gene is upregulated in hairy cell leukemia (HCL) . Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Annexin A1 / (Hairy Cell Leukemia Marker) (CPTC-ANXA1-1), CF488A conjugate, 0.1mg/mL is BNC882223-100.
Annexin A1 / (Hairy Cell Leukemia Marker) (CPTC-ANXA1-1), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Annexin A1 / (Hairy Cell Leukemia Marker) (CPTC-ANXA1-1), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Annexin A1 / (Hairy Cell Leukemia Marker) (CPTC-ANXA1-1), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Annexin A1 / (Hairy Cell Leukemia Marker) (CPTC-ANXA1-1), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Annexin A1 / (Hairy Cell Leukemia Marker) (CPTC-ANXA1-1), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e101213/msds/bnc882223-100.pdf.
Annexin A1 belongs to the annexin family. It plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. In resting conditions Annexin A1 is localized to the cytoplasm. Upon activation it is mobilized to the membrane and secreted. Annexin A1 and contains
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
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