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Product details
Catalog number BNC402239-500
Price for BNC402239-500
Size / count 1x 500 µL
Gelsolin (also known as brevin, Actin-depolymerizing factor or ADF), a protein of leukocytes, platelets and other cells, severs Actin filaments in thepresence of submicromolar calcium, thereby isolating cytoplasmic Actin gels. It is a calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping) . It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. Defects in GSN are the cause of amyloidosis type 5 (AMYL5) ; also known as familial amyloidosis Finnish type, typically characterized by cranial neuropathy and lattice corneal dystrophy. Severe systemic disease can develop in some individuals causing peripheral polyneuropathy, amyloid cardiomyopathy, and nephrotic syndrome leading to renal failure. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF640R conjugate, 0.1mg/mL is BNC402239-500.
Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Gelsolin (also known as brevin, Actin-depolymerizing factor or ADF), a protein of leukocytes, platelets and other cells, severs Actin filaments in thepresence of submicromolar calcium, thereby isolating cytoplasmic Actin gels. It is a calcium-regulated, actin-modulating protein that binds to the plu
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
