Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL

Catalog number BNC472239-500

Price for BNC472239-500

Size / count 1x 500 µL

About this product

Gelsolin (also known as brevin, Actin-depolymerizing factor or ADF), a protein of leukocytes, platelets and other cells, severs Actin filaments in thepresence of submicromolar calcium, thereby isolating cytoplasmic Actin gels. It is a calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping) . It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. Defects in GSN are the cause of amyloidosis type 5 (AMYL5) ; also known as familial amyloidosis Finnish type, typically characterized by cranial neuropathy and lattice corneal dystrophy. Severe systemic disease can develop in some individuals causing peripheral polyneuropathy, amyloid cardiomyopathy, and nephrotic syndrome leading to renal failure. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472239-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Actin depolymerizing factor; ADF; AGEL; Brevin; Gsn
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: GSN
Gene ID: 2934
NCBI Gene ID: 522373
UniProt: P06396
Swiss Prot: P06396
Host: Mouse
Species Reactivity: Human
Reactivity: Actin-depolymerizing Factor|Gelsolin
Immunogen: Recombinant human full-length protein
Target Antigen: Actin-depolymerizing Factor | Gelsolin
Clonality: Monoclonal
Clone: CPTC-Gelsolin-1
Type: Primary
Source: Animal
Origin: Animal
Positive Control: MCF cell lysate, Tonsil.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 90 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL?

The catalog number for Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL is BNC472239-500.

What sizes are available for Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL?

Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL in stock?

Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL?

Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b9061270361e10c570/msds/bnc472239-500.pdf.

What is Gelsolin / Actin-depolymerizing Factor (CPTC-Gelsolin-1), CF647 conjugate, 0.1mg/mL used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.