NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2247-500

Price for BNCB2247-500

Size / count 1x 500 µL

About this product

The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP-K) . In humans, NDP kinase A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human C-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2247-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: AWD; GAAD; Granzyme A activated DNase; Metastasis inhibition factor NM23; NB; NBS; NDP kinase A; NM23 long variant; included; NM23H1B; NME/NM23 nucleoside diphosphate kinase 1; NME1-NME2 spliced read-through transcript; included; Non-metastatic protein 23; homolog 1; Nucleoside diphosphate kinase A; Tumor metastatic process-associated protein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NME1
Gene ID: 4830
NCBI Gene ID: 463456
UniProt: P15531
Swiss Prot: P15531
Host: Mouse
Species Reactivity: Human
Reactivity: NDPK-A|nm23-H1|NME1
Immunogen: Recombinant full-length human NME1 protein
Target Antigen: NDPK-A | nm23-H1 | NME1
Clonality: Monoclonal
Clone: CPTC-NME1-2
Type: Primary
Source: Animal
Origin: Animal
Applications: WB (verified)
Positive Control: HepG2 and HeLa whole cell lysates; heart, brain, placenta and lung carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 23 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL?

The catalog number for NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL is BNCB2247-500.

What sizes are available for NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL?

NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL in stock?

NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL?

NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL?

The safety data sheet for NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) (CPTC-NME1-2), Biotin conjugate, 0.1mg/mL used for?

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.