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Product details
Catalog number BNC882248-100
Price for BNC882248-100
Size / count 1x 100 µL
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP) . In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL is BNC882248-100.
NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells.
As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.
Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.
Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.
