NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL

Catalog number BNC882248-500

Price for BNC882248-500

Size / count 1x 500 µL

About this product

The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP) . In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC882248-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: C myc purine binding transcription factor PUF; C-myc purine-binding transcription factor PUF; epididymis secretory sperm binding protein Li 155an; HEL-S-155an; Histidine protein kinase NDKB; ; NDP kinase B; NDPKB; nm23-H2; NM23B; NME/NM23 nucleoside diphosphate kinase 2; nme2; Nucleoside diphosphate kinase B
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NME2
Gene ID: 4831
NCBI Gene ID: 463456
UniProt: P22392
Swiss Prot: P22392
Host: Mouse
Species Reactivity: Human
Reactivity: NDPK-B|nm23-H2|NME2
Immunogen: Recombinant full-length human NME2 protein
Target Antigen: NDPK-B | nm23-H2 | NME2
Clonality: Monoclonal
Clone: CPTC-NME2-2
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: PC3, A549, HeLa, Jurkat cells. Ubiquitously expressed in all tissues.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 17 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL?

The catalog number for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL is BNC882248-500.

What sizes are available for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL?

NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL in stock?

NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL?

NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL?

The safety data sheet for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), CF488A conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.