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Product details

NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2248-500

Price for BNCB2248-500

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Size / count 1x 500 µL

About this product

The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP) . In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2248-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
C myc purine binding transcription factor PUF; C-myc purine-binding transcription factor PUF; epididymis secretory sperm binding protein Li 155an; HEL-S-155an; Histidine protein kinase NDKB; ; NDP kinase B; NDPKB; nm23-H2; NM23B; NME/NM23 nucleoside diphosphate kinase 2; nme2; Nucleoside diphosphate kinase B
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NME2
Gene ID
4831
NCBI Gene ID
463456
UniProt
P22392
Swiss Prot
P22392
Host
Mouse
Species Reactivity
Human
Reactivity
NDPK-B|nm23-H2|NME2
Immunogen
Recombinant full-length human NME2 protein
Target Antigen
NDPK-B | nm23-H2 | NME2
Clonality
Monoclonal
Clone
CPTC-NME2-2
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
PC3, A549, HeLa, Jurkat cells. Ubiquitously expressed in all tissues.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
17 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL?

The catalog number for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL is BNCB2248-500.

What sizes are available for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL?

NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL in stock?

NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL?

NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL?

The safety data sheet for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e102160/msds/bncb2248-500.pdf.

What is NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), Biotin conjugate, 0.1mg/mL used for?

The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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