• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL

Catalog number BNUB2248-100

Price for BNUB2248-100

Sign In for Pricing

Size / count 1x 100 µL

About this product

The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP) . In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2248-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
C myc purine binding transcription factor PUF; C-myc purine-binding transcription factor PUF; epididymis secretory sperm binding protein Li 155an; HEL-S-155an; Histidine protein kinase NDKB; ; NDP kinase B; NDPKB; nm23-H2; NM23B; NME/NM23 nucleoside diphosphate kinase 2; nme2; Nucleoside diphosphate kinase B
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NME2
Gene ID
4831
NCBI Gene ID
463456
UniProt
P22392
Swiss Prot
P22392
Host
Mouse
Species Reactivity
Human
Reactivity
NDPK-B|nm23-H2|NME2
Immunogen
Recombinant full-length human NME2 protein
Target Antigen
NDPK-B | nm23-H2 | NME2
Clonality
Monoclonal
Clone
CPTC-NME2-2
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
PC3, A549, HeLa, Jurkat cells. Ubiquitously expressed in all tissues.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
17 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL?

The catalog number for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL is BNUB2248-100.

What sizes are available for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL?

NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL in stock?

NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL?

NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL?

Estimated delivery time for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL?

The safety data sheet for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL used for?

The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

You Might Also Like
CD81 / TAPA-1 (1.3.3.22), CF647 conjugate, 0.1mg/mL
CD81 / TAPA-1 (1.3.3.22), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470391-100
TGF-beta (1D11.16.8), CF740 conjugate, 0.1mg/mL
TGF-beta (1D11.16.8), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740977-500
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF594 conjugate, 0.1mg/mL
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF594 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC940679-500
ACTH (Adrenocorticotrophic Hormone) (AH26), CF740 conjugate, 0.1mg/mL
ACTH (Adrenocorticotrophic Hormone) (AH26), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740026-500
CD3e (B-B12), CF640R conjugate, 0.1mg/mL
CD3e (B-B12), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC401052-100
FOXP3 (3G3), CF488A conjugate, 0.1mg/mL
FOXP3 (3G3), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880645-100
CD1a (O10 + C1A/711), CF647 conjugate, 0.1mg/mL
CD1a (O10 + C1A/711), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470717-500
WT1 (Wilm's Tumor 1) (WT1/857), CF405S conjugate, 0.1mg/mL
WT1 (Wilm's Tumor 1) (WT1/857), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040857-100