Product details
Catalog number BNUB2248-100
Price for BNUB2248-100
Size / count 1x 100 µL
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP) . In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL is BNUB2248-100.
NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL is available in the following size(s): 1x 100 µL.
NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL is manufactured by Biotium.
Estimated delivery time for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) (CPTC-NME2-2), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells.
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