Transthyretin (Prealbumin) (CPTC-TTR-1), CF647 conjugate, 0.1mg/mL

About this product

Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC472249-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

Transthyretin; PALB; HsT2651; prealbumin; amyloidosis type 1; ATTR; TBPA; CTS; CTS1; carpal tunnel syndrome 1; thyroxine-binding prealbumin; prealbumin; HEL111; TTR protein; Epididymis luminal protein 111; prealbumin thyroxine binding; senile systemic amyloidosis antibody

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

TTR

Gene ID

7276

NCBI Gene ID

427202

UniProt

P02766

Swiss Prot

P02766

Host

Mouse

Species Reactivity

Human

Reactivity

Transthyretin

Immunogen

Recombinant human full-length protein

Target Antigen

Transthyretin

Clonality

Monoclonal

Clone

CPTC-TTR-1

Type

Primary

Source

Animal

Origin

Animal

Applications

WB (verified)

Positive Control

HepG2, Pancreas and liver.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

15 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG2a, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF647