Aldo-keto Reductase Family 1 Member B1 (Adrenal Marker) (CPTC-AKR1B1-3), 1mg/mL

About this product

Aldo-keto Reductase Family 1 Member B1 (AKR1B1), also known as aldose reductase or aldehyde reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNUM2256-50

Size / count

1x 50 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

Aldo-keto reductase family 1 member B1; AKR1B1; Aldehyde Reductase 1; Aldose reductase; Lii5-2 CTCL tumor antigen; low Km aldose reductase

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

AKR1B1

Gene ID

231

NCBI Gene ID

521212

UniProt

P15121

Swiss Prot

P15121

Host

Mouse

Species Reactivity

Human

Reactivity

Aldo-keto Reductase Family 1 Member B1

Immunogen

Recombinant human full-length AKR1B1 protein

Target Antigen

Aldo-keto Reductase Family 1 Member B1

Clonality

Monoclonal

Clone

CPTC-AKR1B1-3

Type

Primary

Source

Animal

Origin

Animal

Applications

IF (verified) |IHC, FFPE (verified) |WB (verified)

Positive Control

293T, HEK293; A431, HeLa, HepG2, MOLT4, Jurkat and Raji whole cell lysates; Human Kidney; Human colon carcinoma tissue.

Stability

2 years

Concentration

1 mg/mL

Buffer

PBS, no BSA, no azide

Molecular Weight

37 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse)

Classification

PBS, no BSA, no sodium azide (CAS 26628-22-8)

Conjugate

Purified, BSA-free