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Product details
Catalog number BNC042259-100
Price for BNC042259-100
Size / count 1x 100 µL
PTPN6, which is also designated as SHP-1, is expressed primarily in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. It maps to 12p13, a region commonly involved in leukemia-associated chromosomal abnormalities. SHP-1 plays a role in modulating intracellular signaling for various molecules. In T-cell lymphomas and other malignancies, SHP-1 phosphatase expression is lost, by a thus far undetermined mechanism. Preliminary studies suggest that it may be helpful in differentiating mantle/marginal zone lymphomas (SHP-1) from follicular lymphomas (SHP-1 negative) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), CF405S conjugate, 0.1mg/mL is BNC042259-100.
Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e101456/msds/bnc042259-100.pdf.
PTPN6, which is also designated as SHP-1, is expressed primarily in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. It maps to 12p13, a region commonly involved in leukemia-associated chromosomal abnormalities. SHP-1 plays a role in modulating i
Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.
