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Product details

Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL

Catalog number BNUM2259-50

Price for BNUM2259-50

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Size / count 1x 50 µL

About this product

PTPN6, which is also designated as SHP-1, is expressed primarily in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. It maps to 12p13, a region commonly involved in leukemia-associated chromosomal abnormalities. SHP-1 plays a role in modulating intracellular signaling for various molecules. In T-cell lymphomas and other malignancies, SHP-1 phosphatase expression is lost, by a thus far undetermined mechanism. Preliminary studies suggest that it may be helpful in differentiating mantle/marginal zone lymphomas (SHP-1) from follicular lymphomas (SHP-1 negative) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM2259-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
PTPN6; SHP1; protein tyrosine phosphatase; non-receptor type 6; HCP; HCPH; HPTP1C; PTP-1C; SH-PTP1; SHP-1; SHP-1L; 70 kda SHP-1L protein; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; protein-tyrosine phosphatase 1C; PTPN6 / SHP
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PTPN6
Gene ID
5777
NCBI Gene ID
63489
UniProt
P29350
Swiss Prot
P29350
Host
Mouse
Species Reactivity
Human
Reactivity
Protein Tyrosine Phosphatase, non-receptor type 6
Immunogen
Recombinant human full-length PTPN6 protein
Target Antigen
Protein Tyrosine Phosphatase, non-receptor type 6
Clonality
Monoclonal
Clone
CPTC-PTPN6-2
Type
Primary
Source
Animal
Origin
Animal
Positive Control
A431, Jurkat or K562 cell lysates; Lymph node or spleen.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
65 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL?

The catalog number for Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL is BNUM2259-50.

What sizes are available for Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL?

Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL in stock?

Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL?

Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL?

Estimated delivery time for Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL?

The safety data sheet for Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Protein Tyrosine Phosphatase, non-receptor type 6 (CPTC-PTPN6-2), 1mg/mL used for?

PTPN6, which is also designated as SHP-1, is expressed primarily in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. It maps to 12p13, a region commonly involved in leukemia-associated chromosomal abnormalities. SHP-1 plays a role in modulating i

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

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