Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL

Catalog number BNC682268-500

Price for BNC682268-500

Size / count 1x 500 µL

About this product

In contrast to growth factors which promote cell proliferation, FAS ligand (FAS-L) and the tumor necrosis factors (TNFs) rapidly induce apoptosis. Cellular response to FAS-L and TNF is mediated by structurally related receptors containing a conserved 'death domain' and belonging to the TNF receptor superfamily. TRADD, FADD and RIP are FAS/TNF-RI interacting proteins that contain a death domain homologous region (DDH) . TRADD (TNF-RI-associated death domain) and FADD (FAS-associated death domain) associate with the death domains of both FAS and TNF-RI via their DDH regions, while RIP associates exclusively with FAS. An additional FAS interacting protein designated FAF1, for FAS-associated protein factor-1, binds with the cytoplasmic tail of wildtype but not LPR mutant FAS. When overexpressed in cells, FAF1 enhances the efficiency of FAS-mediated apoptosis. In contrast to TRADD, FADD and RIP, FAF1 lacks a DDH and cannot induce apoptosis independently of FAS activation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC682268-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CGI-03; FAS-associated factor 1; HFAF1s; UBX domain-containing protein 12; UBX domain-containing protein 3A
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FAF1
Gene ID: 11124
NCBI Gene ID: 530402
UniProt: Q9UNN5
Swiss Prot: Q9UNN5
Host: Mouse
Species Reactivity: Human
Reactivity: Fas associated factor 1
Immunogen: Recombinant human full-length FAF1 protein
Target Antigen: Fas associated factor 1
Clonality: Monoclonal
Clone: CPTC-FAF1-2
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: HEK293, MCF-7, HeLa whole cell lysate. Human testis, prostate, breast carcinoma or colon carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 75-80 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL?

The catalog number for Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL is BNC682268-500.

What sizes are available for Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL?

Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL in stock?

Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL?

Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ad061270361e10861a/msds/bnc682268-500.pdf.

What is Fas (TNFRSF6) associated factor 1 (CPTC-FAF1-2), CF568 conjugate, 0.1mg/mL used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.