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Product details

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL

Catalog number BNC402271-500

Price for BNC402271-500

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Size / count 1x 500 µL

About this product

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD) . Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. MBD1 has also been predicted to be involved in the development and progression of tumors, and it has been shown that MBD1 is significantly upregulated in pancreatic cancer tissues when compared with surrounding normal tissues. Furthermore, MBD1 may serve as a potential therapeutic target for pancreatic cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC402271-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CXXC-type zinc finger protein 3; CXXC3; MBD1; MECP1 COMPLEX; Methyl-CpG-binding domain protein 1 (MBD1) ; Protein containing methyl-CpG-binding domain 1 (PCM1) ; Regulator of fibroblast growth factor 2 (FGF 2) transcription (RFT)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MBD1
Gene ID
4152
NCBI Gene ID
405610
UniProt
Q9UIS9
Swiss Prot
Q9UIS9
Host
Mouse
Species Reactivity
Human
Reactivity
MBD1
Immunogen
Recombinant human MBD1 protein
Target Antigen
MBD1
Clonality
Monoclonal
Clone
CPTC-MBD1-1
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Human tonsil or colon (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~80 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL?

The catalog number for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL is BNC402271-500.

What sizes are available for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL?

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL in stock?

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL?

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL?

The safety data sheet for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF640R conjugate, 0.1mg/mL used for?

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD) . Each of these proteins,

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

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