Product details
Catalog number BNC942271-100
Price for BNC942271-100
Size / count 1x 100 µL
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD) . Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. MBD1 has also been predicted to be involved in the development and progression of tumors, and it has been shown that MBD1 is significantly upregulated in pancreatic cancer tissues when compared with surrounding normal tissues. Furthermore, MBD1 may serve as a potential therapeutic target for pancreatic cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is BNC942271-100.
MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD) . Each of these proteins,
We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.
Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.
A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.