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Product details

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL

Catalog number BNC942271-100

Price for BNC942271-100

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Size / count 1x 100 µL

About this product

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD) . Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. MBD1 has also been predicted to be involved in the development and progression of tumors, and it has been shown that MBD1 is significantly upregulated in pancreatic cancer tissues when compared with surrounding normal tissues. Furthermore, MBD1 may serve as a potential therapeutic target for pancreatic cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC942271-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CXXC-type zinc finger protein 3; CXXC3; MBD1; MECP1 COMPLEX; Methyl-CpG-binding domain protein 1 (MBD1) ; Protein containing methyl-CpG-binding domain 1 (PCM1) ; Regulator of fibroblast growth factor 2 (FGF 2) transcription (RFT)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MBD1
Gene ID
4152
NCBI Gene ID
405610
UniProt
Q9UIS9
Swiss Prot
Q9UIS9
Host
Mouse
Species Reactivity
Human
Reactivity
MBD1
Immunogen
Recombinant human MBD1 protein
Target Antigen
MBD1
Clonality
Monoclonal
Clone
CPTC-MBD1-1
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Human tonsil or colon (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~80 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL?

The catalog number for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is BNC942271-100.

What sizes are available for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL?

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL in stock?

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL?

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL?

The safety data sheet for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL used for?

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD) . Each of these proteins,

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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