MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL

Catalog number BNC942271-500

Price for BNC942271-500

Size / count 1x 500 µL

About this product

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD) . Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. MBD1 has also been predicted to be involved in the development and progression of tumors, and it has been shown that MBD1 is significantly upregulated in pancreatic cancer tissues when compared with surrounding normal tissues. Furthermore, MBD1 may serve as a potential therapeutic target for pancreatic cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC942271-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CXXC-type zinc finger protein 3; CXXC3; MBD1; MECP1 COMPLEX; Methyl-CpG-binding domain protein 1 (MBD1) ; Protein containing methyl-CpG-binding domain 1 (PCM1) ; Regulator of fibroblast growth factor 2 (FGF 2) transcription (RFT)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MBD1
Gene ID: 4152
NCBI Gene ID: 405610
UniProt: Q9UIS9
Swiss Prot: Q9UIS9
Host: Mouse
Species Reactivity: Human
Reactivity: MBD1
Immunogen: Recombinant human MBD1 protein
Target Antigen: MBD1
Clonality: Monoclonal
Clone: CPTC-MBD1-1
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human tonsil or colon (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~80 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL?

The catalog number for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is BNC942271-500.

What sizes are available for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL?

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL in stock?

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL?

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL?

The safety data sheet for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), CF594 conjugate, 0.1mg/mL used for?

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.