MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2271-100

Price for BNCB2271-100

Size / count 1x 100 µL

About this product

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD) . Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. MBD1 has also been predicted to be involved in the development and progression of tumors, and it has been shown that MBD1 is significantly upregulated in pancreatic cancer tissues when compared with surrounding normal tissues. Furthermore, MBD1 may serve as a potential therapeutic target for pancreatic cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2271-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CXXC-type zinc finger protein 3; CXXC3; MBD1; MECP1 COMPLEX; Methyl-CpG-binding domain protein 1 (MBD1) ; Protein containing methyl-CpG-binding domain 1 (PCM1) ; Regulator of fibroblast growth factor 2 (FGF 2) transcription (RFT)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MBD1
Gene ID: 4152
NCBI Gene ID: 405610
UniProt: Q9UIS9
Swiss Prot: Q9UIS9
Host: Mouse
Species Reactivity: Human
Reactivity: MBD1
Immunogen: Recombinant human MBD1 protein
Target Antigen: MBD1
Clonality: Monoclonal
Clone: CPTC-MBD1-1
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human tonsil or colon (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~80 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL?

The catalog number for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL is BNCB2271-100.

What sizes are available for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL?

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL in stock?

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL?

MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL?

The safety data sheet for MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MBD1 (Methyl-CpG Binding Domain Protein 1) (CPTC-MBD1-1), Biotin conjugate, 0.1mg/mL used for?

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.