Product details
Catalog number BNUM2275-50
Price for BNUM2275-50
Size / count 1x 50 µL
This MAb recognizes a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk's and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for P21WAF1 (Tumor Suppressor Protein) (CIP1/2275R), 1mg/mL is BNUM2275-50.
P21WAF1 (Tumor Suppressor Protein) (CIP1/2275R), 1mg/mL is available in the following size(s): 1x 50 µL.
P21WAF1 (Tumor Suppressor Protein) (CIP1/2275R), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
P21WAF1 (Tumor Suppressor Protein) (CIP1/2275R), 1mg/mL is manufactured by Biotium.
Estimated delivery time for P21WAF1 (Tumor Suppressor Protein) (CIP1/2275R), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for P21WAF1 (Tumor Suppressor Protein) (CIP1/2275R), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
This MAb recognizes a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk's and a tumor suppressor involved in the pathogenesis of a va
Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.
Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.
Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.