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Product details
Catalog number BNC042283-100
Price for BNC042283-100
Size / count 1x 100 µL
This antibody recognizes the Calcineurin A alpha protein, encoded by the PPP3CA (Protein Phosphatase 3 Catalytic Subunit Alpha) gene. Calcineurin is an enzyme that dephosphorylates serine and threonine residues in proteins. It is a heterodimer of a 59 kDa catalytic A subunit and a 19 kDa regulatory B subunit that is activated by the binding of calcium ions and calmodulin. Calcineurin is expressed in many tissues, but its levels are highest in the brain, where it may play a role in learning and memory. It has many substrates, including NFAT, a transcription factor that is activated by dephosphorylation. Complexes of the immuno-suppressants cyclosporine and FK506 with immunophilin proteins such as cyclophilin and FKBP12 are potent and specific inhibitors of Calcineurin activity. Alterations in Calcineurin activity are suspected to play a role in cardiac hypertrophy and graft versus host disease in organ transplantation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Calcineurin A / PPP3CA (BF1.1), CF405S conjugate, 0.1mg/mL is BNC042283-100.
Calcineurin A / PPP3CA (BF1.1), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Calcineurin A / PPP3CA (BF1.1), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Calcineurin A / PPP3CA (BF1.1), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Calcineurin A / PPP3CA (BF1.1), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Calcineurin A / PPP3CA (BF1.1), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
This antibody recognizes the Calcineurin A alpha protein, encoded by the PPP3CA (Protein Phosphatase 3 Catalytic Subunit Alpha) gene. Calcineurin is an enzyme that dephosphorylates serine and threonine residues in proteins. It is a heterodimer of a 59 kDa catalytic A subunit and a 19 kDa regulatory
Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.
Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
