Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2283-500

Price for BNCB2283-500

Size / count 1x 500 µL

About this product

This antibody recognizes the Calcineurin A alpha protein, encoded by the PPP3CA (Protein Phosphatase 3 Catalytic Subunit Alpha) gene. Calcineurin is an enzyme that dephosphorylates serine and threonine residues in proteins. It is a heterodimer of a 59 kDa catalytic A subunit and a 19 kDa regulatory B subunit that is activated by the binding of calcium ions and calmodulin. Calcineurin is expressed in many tissues, but its levels are highest in the brain, where it may play a role in learning and memory. It has many substrates, including NFAT, a transcription factor that is activated by dephosphorylation. Complexes of the immuno-suppressants cyclosporine and FK506 with immunophilin proteins such as cyclophilin and FKBP12 are potent and specific inhibitors of Calcineurin activity. Alterations in Calcineurin activity are suspected to play a role in cardiac hypertrophy and graft versus host disease in organ transplantation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2283-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Calcineurin A; Calcineurin A alpha; PPP3CA; Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; CALN; CALNA1; CAM-PRP catalytic subunit; CCN1; CNA alpha; CNA1; Protein phosphatase 3 catalytic subunit alpha isoform
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PPP3CA
Gene ID: 5530
NCBI Gene ID: 435512
UniProt: Q08209
Swiss Prot: Q08209
Host: Mouse
Species Reactivity: Human
Reactivity: Calcineurin A|PPP3CA
Immunogen: Recombinant full-length Calcineurin A protein
Target Antigen: Calcineurin A | PPP3CA
Clonality: Monoclonal
Clone: BF1.1
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Ion channels
Positive Control: HeLa, MCF-7 or A431 cells. Prostate, Thyroid or Pancreas.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 62 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL?

The catalog number for Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL is BNCB2283-500.

What sizes are available for Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL?

Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL in stock?

Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL?

Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Calcineurin A / PPP3CA (BF1.1), Biotin conjugate, 0.1mg/mL used for?

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.