CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL

Catalog number BNC942291-500

Price for BNC942291-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR) . CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3', 5'-cyclic monophosphate (cAMP) -activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC942291-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ABC35; ATP Binding Cassette Superfamily C Member 7 (ABCC7) ; cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; Cystic Fibrosis Transmembrane Conductance Regulator; MRP7; TNR CFTR
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CFTR
Gene ID: 1080
NCBI Gene ID: 489786, 621460, 661104
UniProt: P13569
Swiss Prot: P13569
Host: Mouse
Species Reactivity: Human, Mouse
Reactivity: CFTR
Immunogen: Recombinant full-length human CFTR protein
Target Antigen: CFTR
Clonality: Recombinant Monoclonal
Clone: RCFTR/1342
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: MOLT-4 cells. Pancreas, Kidney or Placenta.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 165-170 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL?

The catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL is BNC942291-500.

What sizes are available for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL in stock?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL?

The safety data sheet for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), CF594 conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.