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Product details

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL

Catalog number BNUM2291-50

Price for BNUM2291-50

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Size / count 1x 50 µL

About this product

Recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR) . CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3', 5'-cyclic monophosphate (cAMP) -activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM2291-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ABC35; ATP Binding Cassette Superfamily C Member 7 (ABCC7) ; cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; Cystic Fibrosis Transmembrane Conductance Regulator; MRP7; TNR CFTR
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CFTR
Gene ID
1080
NCBI Gene ID
489786, 621460, 661104
UniProt
P13569
Swiss Prot
P13569
Host
Mouse
Species Reactivity
Human, Mouse
Reactivity
CFTR
Immunogen
Recombinant full-length human CFTR protein
Target Antigen
CFTR
Clonality
Recombinant Monoclonal
Clone
RCFTR/1342
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
MOLT-4 cells. Pancreas, Kidney or Placenta.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
165-170 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL?

The catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL is BNUM2291-50.

What sizes are available for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL in stock?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL?

Estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL?

The safety data sheet for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (rCFTR/1342), 1mg/mL used for?

Recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR) . CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both a

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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