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Product details

Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL

Catalog number BNUM2298-50

Price for BNUM2298-50

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Size / count 1x 50 µL

About this product

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18) . This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained. Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM2298-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CARD2; CK8; CYK8; CYKER; Cytokeratin Endo A; DreK8; EndoA; K2C8; K8; Keratin 8; Krt 2.8; KRT8; Type-II Keratin Kb8. Cell Proliferation-inducing Gene 46 Protein; CK18; CYK18Cytokeratin Endo B; K18; Keratin-18; Kerd; KRT18
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT8; KRT18
Gene ID
3856; 3875
NCBI Gene ID
533782; 708445; 406013
UniProt
P05787; P05783
Swiss Prot
P05787; P05783
Host
Mouse
Species Reactivity
Human
Reactivity
Cytokeratin 8/18
Immunogen
Recombinant full-length human KRT8 protein & Recombinant full-length human KRT18 protein
Target Antigen
Cytokeratin 8/18
Clonality
Recombinant Monoclonal
Clone
RKRT8.18/1346
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
MCF-7 or A431 cells. Skin, Colon, lung or breast carcinoma
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
52.5 kDa (CK8) ; 45 kDa (CK18)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL?

The catalog number for Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL is BNUM2298-50.

What sizes are available for Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL?

Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL in stock?

Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL?

Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL?

Estimated delivery time for Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL?

The safety data sheet for Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin 8/18 (rKRT8.18/1346), 1mg/mL used for?

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18) . This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tra

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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