Product details
Catalog number BNC682306-500
Price for BNC682306-500
Size / count 1x 500 µL
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (rMMP3/1730), CF568 conjugate, 0.1mg/mL is BNC682306-500.
MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (rMMP3/1730), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (rMMP3/1730), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (rMMP3/1730), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (rMMP3/1730), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (rMMP3/1730), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b4061270361e10ab80/msds/bnc682306-500.pdf.
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (L
Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.
A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.