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Product details
Catalog number BNUM2311-50
Price for BNUM2311-50
Size / count 1x 50 µL
SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas.In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for SOX10 (Melanoma Marker) (SOX10/2311R), 1mg/mL is BNUM2311-50.
SOX10 (Melanoma Marker) (SOX10/2311R), 1mg/mL is available in the following size(s): 1x 50 µL.
SOX10 (Melanoma Marker) (SOX10/2311R), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
SOX10 (Melanoma Marker) (SOX10/2311R), 1mg/mL is manufactured by Biotium.
Estimated delivery time for SOX10 (Melanoma Marker) (SOX10/2311R), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for SOX10 (Melanoma Marker) (SOX10/2311R), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101f6e/msds/bnum2311-50.pdf.
SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conven
Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
