ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL

Catalog number BNC042318-500

Price for BNC042318-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 110 kDa, identified as Excision Repair Cross Complementing 1 (ERCC1) . It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV) -induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC042318-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: COFS4; DNA excision repair protein ERCC1; ERCC1; Excision repair cross complementing 1; RAD10; UV20
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ERCC1
Gene ID: 2067
NCBI Gene ID: 435981
UniProt: P07992
Swiss Prot: P07992
Host: Mouse
Species Reactivity: Human
Reactivity: ERCC1|RAD10
Immunogen: Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary)
Target Antigen: ERCC1 | RAD10
Clonality: Monoclonal
Clone: ERCC1/2318
Type: Primary
Source: Animal
Origin: Animal
Positive Control: HeLa, HepG2 cells. Tonsil or Prostate.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~110 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL?

The catalog number for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL is BNC042318-500.

What sizes are available for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL in stock?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL?

The safety data sheet for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF405S conjugate, 0.1mg/mL used for?

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.